Patents

"NAPHTHOFURANONE DERIVATIVES AS SPECIFIC INHIBITORS OF THYMIDYLATE SYNTHASES"

International Application No. PCT/EP 2007/006006

Pub. No. WO/2008/003510

United States Patent Application 20100048692

  •  The present invention relates to 1,2-naphthalein moelcules having specific inhibitory properties of the enzymatic activity of thymidylate synthases of bacterial species, their preparation, their pharmaceutical composition and use in the treatment and prophylaxis of infectious pathologies are disclosed.

"SPECIFIC INHIBITORS OF PTERIDINE REDUCTASE WITH ANTIPARASITIC ACTION"

International Application No. PCT/EP2008/011106

Pub. No. WO/2009/080367

  •  The present invention relates to 4-(heteroaryl)aminobenzoyl derivative compounds, to processes for their preparation, to pharmaceutical compositions containing them, and to the use of said compounds as synergistic agents in the manufacture of pharmaceutical compositions for the combination treatment of protozoarian infections, such as, for example, Leihsmaniasis and Tripanosomiasis.